Abstract

MOISES, Torres-Maure, et al. Uso del esquema Scottish and Newcastle Anti-Emetic Pretreatment (SNAP) en la recuperación de una intoxicación por sobredosis masiva de acetaminofén (paracetamol) con injuria hepática aguda - Reporte de caso. Rev. gastroenterol. Perú [online]. 2023, vol.43, n.1, pp.53-56.  Epub Apr 11, 2023. ISSN 1022-5129.  http://dx.doi.org/10.47892/rgp.2023.431.1400.

Acetaminophen is a drug widely used in the world and easily accessible due to its antipyretic, analgesics characteristics, among others (1); however, exposure to toxic doses causes organic damage and even death. We present the case of an 18-year-old female patient who ingested 40 grams of acetaminophen and developed severe liver dysfunction, being treated with N-acetylcysteine (NAC) antidotal therapy according to the simplified scheme: Scottish and Newcastle Anti-emetic Pretreatment Paracetamol Poisoning Study Regimen (SNAP), presenting improvement in the clinical course and decrease in liver profiles, coagulation disorder, INR and resolution of the condition.

Keywords : Acetaminophen; Poisoning; Acetylcysteine; Chemical and Drug Induced Liver Injury; Liver Failure.

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