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Revista de Gastroenterología del Perú
Print version ISSN 1022-5129
Abstract
LI SALVATIERRA, Bruno; CALIXTO-AGUILAR, Lesly; RAMOS-CASTILLO, Wilder and CHACALTANA MENDOZA, Alfonso. Effectiveness and safety of endosonography-guided liver biopsy in liver disease at a level III public hospital. Rev. gastroenterol. Perú [online]. 2023, vol.43, n.4, pp.341-347. Epub Dec 20, 2023. ISSN 1022-5129. http://dx.doi.org/10.47892/rgp.2023.434.1592.
Parenchymal liver diseases are commonly evaluated by laboratory and imaging studies. However, in some cases a liver biopsy is required. Endoscopic ultrasonography-guided liver biopsy (EUS-LB) has been reported as a procedure with high diagnostic yield (90-100%) with low adverse event profile, but there are not studies which report about the experience and technique in our country.
Objective:
Determinate the effectiveness and the safety of endosonography-guided liver biopsy in liver parenchymal disease.
Materials and methods:
A prospective study was conducted at a III-2 level of care Public Hospital in Lima, Peru. It included patients over 18 years of age with suspicion of parenchymal liver disease who underwent EUS-LB for study hepatic parenchymal disease since March of 2018 to October of 2022.
Results:
The diagnostic yield of the biopsies was 77.02%, with a mean length of the sample of 13.98mm (standard deviation 7.34) and a median of 8 complete portal spaces (0-50). Only 31.25% of the procedures were performed with a fine needle biopsy (FNB), finding a significant difference between the type of needle and the diagnostic yield (p=0.01). The most common histopathological diagnosis was autoinmune hepatitis. There were 2.08% of post-procedure complications.
Conclusions:
EUS-LB for the diagnosis of liver parenchymal disease had a diagnostic yield close to 80% in our region with a low profile of adverse events. However, more prospectives studies with a larger number of patients are required.
Keywords : Endosonography; Liver; Biopsy, fine-needle aspiration; Biopsy, fine-needle.
