Resumo

PACHECO ROMERO, José. Endothelial dysfunction in pre-eclampsia. An. Fac. med. [online]. 2003, vol.64, n.1, pp.43-54. ISSN 1025-5583.

We still do not know the etiology of pre-eclampsia. We do know now that it is not only a pregnancy induced hypertension, but an interaction between decreased placental perfusion and deep maternal endothelial function alteration, probably due to immune reasons favouring partial alteration of normal implantation. Maternal contribution is of factors that predate pregnancy influenced by the usual metabolic adaptations. There is no single gene to explain preeclampsia, but looking for maternal predisposition may prevent pre-eclampsia in a group of women.

Palavras-chave : Pre-eclampsia; eclampsia; endothelium; perfusion; placentation.

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