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Anales de la Facultad de Medicina

Print version ISSN 1025-5583


AREVALO, Fernando  and  CABANILLAS, José. Tuberculous lymphadenitis in HIV infection: Histological findings. An. Fac. med. [online]. 2006, vol.67, n.3, pp.230-234. ISSN 1025-5583.

Introduction: Coinfection of human virus immunodeficiency (VIH) and tuberculosis changes the histological features of tuberculosis; this is particularly frequent in tuberculous lymphadenitis. Objective: To identify main histological diferences between tuberculous lymphadenitis associated to VIH and not associated to VIH. Design: Descriptive, transversal, comparative stufy. Setting: Pathological Anatomy Service, Dos de Mayo Hospital. Participants: Patients with tuberculous lymphadenitis associated or not to VIH. Interventions: Study of histological differences between lymphadenitis tuberculosis associated with HIV and non associated with HIV, during 2005 and first half of 2006. Main outcome measures: Histological presentation of tuberculosis. Results: Twenty-two cases of tuberculous lymphadenitis were identified, 27,3% showed VIH coinfection; caseum necrosis was identified in 83,3% of cases HIV-associated and in 100% of non-HIV associated cases (p=0,00). Koch bacillus was identified in 50% of associated HIV cases and it was not identified in any non related HIV case (p=0,01). We also found an attributable risk of 52,3% for the development of caseum necrosis and presence of Langhans cells. Conclusions: We found higher presence of mycobacterium in HIV positive patients and higher presence of caseum necrosis in HIV negative patients.

Keywords : Tuberculosis, lymphanode; HIV; necrosis; giant cells, Langhans.

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