SciELO - Scientific Electronic Library Online

vol.74 issue1Relationship between dietary cholesterol, egg consumption and lipid profile in apparently healthy adults according to age groupVariability and reliability of times registered for cesarean delivery surgical processes at a private clinic, Lima, Peru, 2011 author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Anales de la Facultad de Medicina

Print version ISSN 1025-5583


GUEVARA-SILVA, Erik. Cognitive profile in human immunodeficiency virus-infected neurologically asymptomatic patients. An. Fac. med. [online]. 2013, vol.74, n.1, pp.31-36. ISSN 1025-5583.

Background: Several studies have reported cognitive impairment in HIV-1 infected individuals even at early stages of the infection. Short-term memory, psychomotor speed, attention and executive functions are mainly affected. Objectives: To determine the cognitive profile in neurologically asymptomatic HIV-infected patients before starting highly active antiretroviral therapy (HAART), and possible associated factors. Design: Analytic and cross-sectional study. Setting: Hospital Regional de Huacho, Peru. Participants: HIV patients with criteria to start HAART. Interventions: Twenty-one asymptomatic HIV patients attended from April to July 2011 had a detailed clinical history and a battery of standardized neuropsychological tests. Main outcomes measures: Scores in psychomotor speed, executive function, immediate memory, attention, and visuospatial performance evaluations. Results: Significant cognitive impairment was determined in 47.6% of patients. Patients performed worse in psychomotor speed and executive function tests. All but one patient failed at least in one test. Age, level of instruction, time of disease, and depression were not statistically associated. Conclusions: In accordance with the literature, these findings suggest cognitive decline may occur in early asymptomatic stages of HIV infection.

Keywords : Cognitive impairment; cognitive profile; human immunodeficiency virus; neuropsychological test.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )