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Anales de la Facultad de Medicina

Print version ISSN 1025-5583


RODRIGUEZ, Javier et al. Exponential chaotic law of cardiac dynamical systems for Holter evaluation: 16 hours. An. Fac. med. [online]. 2017, vol.78, n.3, pp.292-297. ISSN 1025-5583.

Introduction: In a previous study, a 16-hour reduction in the evaluation of the exponential law of chaotic cardiac dynamics was done, showing its effectiveness in the characterization of disease and normality. Objective: To confirm the clinical applicability of the exponential mathematical law to evaluate chaotic cardiac dynamics from the Holter registers in 16 hours, observing its diagnostic utility when reducing its evaluation time. Design: Cross-sectional observational study where the electrocardiographic parameters were evaluated using inductive mathematical methodologies with statistical confirmation. Methodology: We obtained 100 Holter records from patients with different types of pathology, and 40 Holter that were diagnosed as normal. For each Holter, a chaotic attractor was constructed, and measuring their spaces of occupation and fractal dimension, the mathematical evaluation to differentiate normality of disease was applied. Finally, we calculated measures of diagnostic concordance in accordance with the gold standard. Results: The spatial occupation of all the attractors was within the expected values; the normal records had values in the Kp grid between 205 and 423. For the records with acute disease, these values ranged from 21 y 65; and for chronic disease registries these values ranged from 104 y 195. The values of sensitivity and specificity were 100% and the Kappa coefficient was 1. Conclusion: The present study shows the clinical applicability of this methodology for the evaluation in 16 hours of continuous electrocardiographic or Holter registers.

Keywords : Law; Chaos; Chaotic Law; Fractal, Cardiac Dynamics; Diagnosis.

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