Abstract

CORAS, Natalia; PULIDO, Alfredo  and  RODRIGUEZ, Cindy. Acute exantematic pustulosis generalized acute indicated by meropenem. An. Fac. med. [online]. 2019, vol.80, n.4, pp.503-506. ISSN 1025-5583.  http://dx.doi.org/10.15381/anales.v80i4.16742.

We present the case of a 91-year-old female, patient hospitalized for operative wound infection secondary to hip surgery. Antibiotic treatment with meropenem was administered, presenting at 4 days: fever, asthenia and disseminated erythematous rash with non-follicular pustules predominantly of the trunk, extremities and fold areas; In addition, leukocytosis is found with neutrophilia. Histopathological study of skin biopsy showed subcorneal pustules with exocytosis of neutrophils. Antibiotic was discontinued, with clinical improvement 5 days after the suspension of meropenem. There are few reports of cases of acute generalized exanthematous pustulosis caused by meropenem.

Keywords : Meropenem; Acute Generalized Exanthematous Pustulosis; Exanthema.

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