Abstract

RAMIREZ, Juan; NORENA-BUITRON, Lizeth  and  ESTELA-ZAPE, Jose. Fatal outcome in coinfection between SARS-CoV-2 and dengue. An. Fac. med. [online]. 2023, vol.84, n.4, pp.448-452.  Epub Dec 30, 2023. ISSN 1025-5583.  http://dx.doi.org/10.15381/anales.v84i4.26855.

COVID-19, a result of SARS-CoV-2 infection, is characterized by a primary impact on the alveolar cells of the respiratory system. However, the possibility of co-infection with dengue virus (DENV) has been documented, triggering a severe systemic inflammatory response. This heightened inflammatory response leads to a substantial release of viral RNA into the cellular cytoplasm, which amplifies the viral load and aggravates lung damage, causing multiple organ dysfunction. In the case of DENV, the infection induces a cytokine storm that increases capillary permeability, resulting in plasma leakage. The present report aims to describe a case of an adult male patient with COVID-19 and dengue co-infection who had a fatal outcome.

Keywords : COVID-19; Dengue; Coinfection; Immunity.

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