Resumo

SANCHEZ R., Alfonso; ROJAS C., Gonzalo  e  MORENO M., Paloma. Interruption of gestation in a bitch using a combined treatment of cloprostenol and cabergoline. Rev. investig. vet. Perú [online]. 2010, vol.21, n.1, pp.130-135. ISSN 1609-9117.

The effectiveness of a combined treatment of cloprostenol and cabergoline was evaluated for interruption of gestation in bitches. A clinical experience is reported in an English bulldog bitch with a gestation of 30 days. The treatment was administrated every 24 hours and consisted in 5 µg/kg of cabergoline, orally, followed 30 minutes later by 1 µg/kg of cloprostenol, via subcutaneous. Physiological constants, effects post administration, and ecographic evolution of the gestation was evaluated. Also, progesterone concentration was determined in two blood samples using a quantitative commercial kit. Changes in gestational vesicles were observed at day 3 of treatment, and a lower cardiac frequency (<180 bpm) were recorded on day 4. A fetal expulsion occurred few hours later. Ultrasound on day 5 showed absence of vesicles and fetuses. Serum progesterone concentration on day 3 was 1 to 2.5 ng/ml, incompatible with the maintenance of gestation, and on day 5 was <1 ng/ml. The results allowed confirming the effectiveness of this protocol to interrupt gestations in bitches, highlighting the short duration of the treatment (4 days).

Palavras-chave : bitch; termination of pregnancy; cloprostenol; cabergoline.

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