Abstract

MORALES B., Abelardo et al. Gastric, liverand renal lesions associated to the syndrome of gastric ulcers in thoroughbred horses. Rev. investig. vet. Perú [online]. 2011, vol.22, n.2, pp.133-137. ISSN 1609-9117.

The aim of this study was to describe gastric, hepatic, and renal lesions in Thoroughbred Racing horses associated to the equine gastric ulcer syndrome. Thirty horses with a history of gastric ulcer syndrome and recurrent colic during 2006 to 2007 at the Race Track «La Rinconada», Caracas, Venezuela were evaluated. Horses were euthanized and the necropsy was conducted. Tissue samples were collected from stomach, liver and kidney, and processed by conventional histological methods. In the stomach, the mucosa was intact but areas of hyperaemia and hyperkeratosis were observed in 6 cases, multifocal small erosions or ulcers in 6 cases, multifocal large ulcers with areas of extensive erosion in 12 cases and extensive areas of ulceration with exposure of the submucosa in 6 cases. The macroscopic evaluation of the liver showed evident hepatomegaly in 22 cases and lobular pattern in 18 cases. The kidneys showed severe congestion in all cases, loss of cortico-medullar ratio in 20 cases, cortical necrosis in 18 cases, acute tubular necrosis in all cases, papillary necrosis in 6 cases, and adherence of the capsule with interstitial fibroplasia in 4 cases. Lesions in the gastric mucosa, liver and kidney were associated with extended treatment with non-steroidal anti-inflammatory drugs.

Keywords : equine; pathology; gastritis; digestive; liver; kidney; equine gastric ulcer syndrome.

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