Abstract

SANCHEZ, María del Pilar et al. Rabies in the Americas, various challenges and «One Health: Review article. Rev. investig. vet. Perú [online]. 2019, vol.30, n.4, pp.1361-1381. ISSN 1609-9117.  http://dx.doi.org/10.15381/rivep.v30i4.17149.

abies is caused by a neurotropic virus of negative RNA chain belonging to the genus Lyssavirus, family Rhabdoviridae, Mononegavirals order. The rabies-causing species in the Americas is the Lyssavirus RABV with 11 antigenic variants. Humanrabies deaths have been drastically reduced in the United States over the past decade, yet cases of rabies are reported in dogs and cats infected by wild mammals. In Canada, as in the United States, the most common species of rabies reservoirs are wild mammals, mainly bats, skunks and foxes. Rabies is endemic in most of the Canadian Arctic, caused by the Arctic Rabies Virus variant. In North America, cross-species transmission has been observed. Wildlife control is carried out by oral bait vaccine, authorized in raccoons and coyotes. In Latin America and the Caribbean, canine rabies has declined by 98% and human rabies transmitted by dogs is in the way of elimination. In spite of this, Latin America faces a complex situation due to the re-emergence of canine rabies in areas declared free, emergence of human rabies transmitted by cats associated with variant 3 «Vampire», increase in wild rabies in cattle, and still a high incidence of human rabies transmitted by dogs in countries like Bolivia and Haiti. As these challenges involve people, animals and ecosystems, control strategies must be different from those applied to human rabies only. The One Health approach, which takes into account these three elements, and implies changes from the conducting an anti-rabies campaign, the way of analysing epidemiological and biomolecular data of the virus, will be essential in the search for zero human deaths, containment of wild rabies and regional elimination of canine and feline rabies.

Keywords : rabies virus; viral variants; bats; rabies transmission; human rabies.

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