Abstract

HOLGUIN-CESPEDES, Gisella Karina  and  DIAZ-RIVERA, Edgar. Anthelmintic resistance in sheep farms of the warm valle y of Alto Magdalena - Tolima. Rev. investig. vet. Perú [online]. 2023, vol.34, n.1, e24591.  Epub Feb 27, 2023. ISSN 1609-9117.  http://dx.doi.org/10.15381/rivep.v34i1.24591.

The aim of this study was to determine the degree of anthelmintic resistance of nematodes that affect sheep production in the warm valley of Alto Magdalena in the department of Tolima, Colombia, using the faecal egg count reduction technique. The study was carried out with 380 sheep in 13 farms. The load of gastrointestinal parasites was determined using the McMaster technique. Sheep with >200 eggs per gram of faeces were randomly assigned to four anthelmintic groups (fenbendazole, moxidectin, ivermectin, and levamisole) and one control group. Samples were collected on day 0 and day 14 postdosing to determine the percentage of drug effectiveness. In addition, larval cultures were performed to determine the species of nematodes present. Anthelmintic resistance was found, especially to Haemonchus spp in 91, 89 and 46% of the farms towards fenbendazole, ivermectin and levamisole, respectively, the most widely used compounds in the region, as well as multi-resistance in 78% of the farms.

Keywords : fenbendazole; ivermectin; levamisole; nematode; nematicides.

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