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Revista Peruana de Medicina Experimental y Salud Publica
Print version ISSN 1726-4634
Abstract
DE LOS SANTOS, Maxy and MONTOYA, Ysabel. Identificación de una nueva proteína en Leishmania (Viannia) peruviana. Rev. perú. med. exp. salud publica [online]. 1998, vol.15, n.1-2, pp.7-11. ISSN 1726-4634.
Nucleotidic and aminoacidic sequence analysis from a clone of a phage λgt11 obtained from a expression vector library of Leishmania (Viannia) peruviana, established partial identity with the genes of the acidic ribosomal proteins P2 of Leishmania (Leishmania) infantum. These molecular findings along with certain conserved genomic domains, suggested by comparison of 14 sequences of eukaryotic P1 proteins, confirmed that the insert of the clone codes for acidic ribosomal protein P1 of L (V) peruviana refered as LpP1. This is the first report about this type of protein in Leishmania genus.
Keywords : Leishmania; leishmaniasis; acidic ribosomal proteins; P-proteins.