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Revista Peruana de Medicina Experimental y Salud Publica

Print version ISSN 1726-4634


CASTRO DE LA MATA, Ramiro  and  ZAVALETA MARTINEZ-VARGAS, Alfonso. Programa en "BASIC" para el cálculo de DL50 por el método de Probits. Rev. perú. med. exp. salud publica [online]. 1998, vol.15, n.1-2, pp.45-54. ISSN 1726-4634.

A program in the languaje BASIC is described, for the MSDOS platform, designed to calculate the Average Lethal Dose (DL50) of toxic agents used in the method of transformation in probits. For using this program, the operator supplies the dose of the toxic reagent used in the lethal acute toxicity test, the number of animals which die with this dose, DL50, as well as the trustworthy limits to give 95% reliability. In addition final and provisional straight line values. The program offers in addition, the possibility of making a re-analysis of the data in the cases in which it is desired to seek a better approximation of the values, graphs, file the results on discs and the option to compare the two curves, for the estimation of relative strengths.

Keywords : DL50; Probits; DE50; Acute toxicity.

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