Abstract

LLANOS-ZAVALAGA, Fernando et al. Evaluación de la prueba ICT Malaria P. f/P.v ( AMRAD ^® ) para la detección de P. falciparum y P. vivax en una zona endémica de la Amazonía peruana. Rev. perú. med. exp. salud publica [online]. 2002, vol.19, n.1, pp.39-42. ISSN 1726-4634.

Objective: To assess the ICT MALARIA P.f/P.v (AMRAD^®) in febrile patients in Loreto Department, Peru. Material and methods: A cross-sectional study performed in febrile (axillary temperature 37.5°C) patients with no apparent cause for the fever, from August to September 2000. A blood sample for performing thick smear examination was obtained. Well-trained personnel performed this test. Also, a field assistant performed the rapid test. Sensitivity, specificity, predictive values, accurateness and concordance index were calculated using the thick blood smear as the gold standard. Results: 79 patients were included (5 months - 70 years of age). Sensitivity and specificity for the AMRAD^® were 60,0 and 70,0%, respectively. Positive predictive value (PPV), negative predictive value (NPV) and accuracy of the test were respectively 36,0, 88,8 and 70,9%. The test had poor concordance with the thick smear test (kappa=0,279). Conclusion: It is necessary to continue assessing rapid testing methods in order to have a timely diagnosis and early therapy for malaria.

Keywords : Malaria/diagnosis; Laboratory tecniques and procedures; Sensitivity and specificity.

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