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Revista Peruana de Medicina Experimental y Salud Publica

Print version ISSN 1726-4634


RAMIREZ RAMOS, Alberto; MENDOZA REQUENA, Daniel; LEEY CASELLA, Julio  and  GUERRA VALENCIA, José. Estudio del Helicobacter pylori en el Perú. Rev. perú. med. exp. salud publica [online]. 2002, vol.19, n.4, pp.209-214. ISSN 1726-4634.

The important contribution of several researchers on the characteristics of H. pylori infection in Peru is shown in this article. Epidemiology: the onset of the infection is at early stages of life. The most important way of trasmission is the fecal-oral route and by water. The prevalence in low socioeconomic population is similar for the coast, mountain and jungle. The prevalence of H. pylori infection is decreasing among medium to high socioeconomic status (related to peptic ulcer and gastric cancer reduction) and it is still constant among people from low socioeconomic status. There is no evidence that a certain race is more susceptible to acquire this infection. The prevalence of chronic atrophic gastritis is higher in people from high altitude areas compared to that people living at sea level. Microbiology, molecular biology and pathology: Peruvian H. pylori strains are similar to those from Spain and Europe and ther are very different from those proceeding from Japan and China. Chronic superficial gastritis, chronic deep gastritis and chronic atrophic gastritis are different stages of the inflammatory injury produced by the bacteria in the stomach. Diagnosis: stomach biopsy using silver staining is the gold standard. The combination of two techniques can be helpful. Treatment: triple drug therapy provides an eradication rate higher than 80%. The use of regimens containing two drugs or one drug are not enough. The rate of postreatment relapse is high and it it mostly produced by a different strain.

Keywords : Helicobacter pylori; Epidemiolog; Diagnosis; Therapy; Peru.

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