Abstract

Perfil etiológico del síndrome febril icterohemorrágico agudo y síndrome febril ictérico agudo en los valles del Apurímac, Quillabamba, Chanchamayo y Alto Huallaga, Perú, 1999-2000.. Rev. perú. med. exp. salud publica [online]. 2003, vol.20, n.3, pp.132-137. ISSN 1726-4634.

Objectives: To know the etiologic profile of acute hemorrhagic febrile sindrome and acute icteric febrile sindrome in Río Apurímac (Ayacucho), Quillabamba (Cusco), Chanchamayo (Junín) y Alto Huallaga (Huánuco) valleys. Materials and methods: Longitudinal descriptive study done between June 1999 and May 2000, in 146 health establishments of the four valleys. There were included patients that completed the criteria of case definitions for acute hemorrhagic febrile sindrome (AHFS) and acute icteric febrile sindrome (AIFS). In the obtained samples were performed IgM ELISA for yellow fever; IgM anti-HBc ELISA y HBsAg ELISA for hepatitis B; Ig anti-VHD ELISA for hepatitis D; and IgM ELISA for leptospirosis. Results: There were included 63 cases: 98.4% with AIFS and 1.6% with AHFS. The letality was 16% and the time between the onset of symptoms and the sample collection was 7.2 ±5,1 days. 31 (49.2%) cases had confirmed diagnosis: hepatitis B (23.8%), hepatitis D (15.6%), yellow fever (4.8%) and leptospirosis (4.8%). Cusco had the greater proportion of confirmed cases by laboratory, the majority hepatitis B and D. Conclusions: The study of the etiology of AHFS and AIFS had permited: to identify 3 outbreaks of yellow fever (in Cusco, Junín and Huánuco), and to know the importance of hepatitis B, D and leptospirosis in the differential diagnosis of these sindromes. Although the definitions helped to detect severe diseases, the surveillance of both sindromes is complementary and totally compatible with the systems of especific disease and by the laboratory.

Keywords : Epidemiologic surveillance; Fever/etiology; Peru.

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