Abstract

SOMOCURCIO, José G. et al. Surgical therapy of multidrug-resistant pulmonary tuberculosis in Peru: report of 304 cases. Rev. perú. med. exp. salud publica [online]. 2009, vol.26, n.3, pp.289-293. ISSN 1726-4634.

Treatment for pulmonary tuberculosis (TB) is drug-based but the emergence of drug-resistance has decreased itstherapeutic efficacy. Pulmonary surgery is an important beneficial adjuvant strategy for MDR TB treatment in this context.Objectives. To describe the clinical characteristics results and complications in a series of 304 patients with MDR TBsubmitted to surgical therapy. Material and methods. Between May of 1999 and January of 2007 a total of 336 surgicalinterventions were performed on 304 patients from the National Program of TB Control who, were operated by a surgicalteam of the Ministry of Health in the Hipolito Unanue National Hospital and in a Private Center in Lima. Results. Mostcases were male (60%) and the mean age was 28 years. Patients were resistant to a median of 5 drugs. Cavitarylesions were the most common (91.8%) and lobectomy was the most commonly performed surgical procedure (68.4%).Postoperative morbidity and mortality occurred in 12.8% and 2% respectively. Patients were followed post-operativelyfor a maximum time of 79.3 months and healing was reached in the 77.2% of cases. Conclusions. Pulmonary adjuvantsurgery on MDR TB patients is an effective alternative for cure. This strategy should be included as part of treatmentprograms for MDR TB.

Keywords : Multidrug-resistant tuberculosis; Thoracic surgery; Pneumonectomy; Pulmonary tuberculosis; Peru.

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