Revista Peruana de Medicina Experimental y Salud Publica
ISSN 1726-4634 versión impresa
MIRANDA, Eduardo, VELARDE, franko, SOMOCURCIO, José et al. Evaluación de dos pruebas de inmunoblot con antígeno hidatídico de caprino y ovino para el diagnóstico de equinococosis humana. Rev. perú. med. exp. salud publica, jun. 2010, vol.27, no.2, p.209-214. ISSN 1726-4634.
To estimate the diagnosis value of goat and ovine antigen for echinococcosis immunoblot test, 135 serums were used, of which 70 were coming from patients with hydatid disease confirmed by the finding of proto scolex and membrane in the pathology study of surgical piece, 45 from patients with other parasitic diseases and 20 apparently healthy people. The sensitivity, the specificity, positive and negative predictive value of immunoblot test, with hidatyd antigen of goat was of 92.8%, 100%, 100%, 92.8%, respectively, than for ovine antigen was 91.4%, 95.3%, 95.5%, 91.1%, respectively. Kappa index was 0.93 for goat antigen and 0.86 with sheep in relation to the pathological study. We recommended the use of both antigens for the serologic diagnosis of human echinococcosis.
Palabras llave: Echinococcosis; Blotting, western; Sensitivity and specificity; Cross-priming.
Instituto Nacional de Salud
Cápac Yupanqui 1400 - Jesús María
Apartado Postal 471
Teléfono : ( 51-1) 4719920 Anexo 162
Fax: ( 51-1) 4717443