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Revista Peruana de Medicina Experimental y Salud Publica
versión impresa ISSN 1726-4634
Resumen
MACHADO-ALBA, Jorge Enrique; ALZATE-CARVAJAL, Verónica y ECHEVERRI-CATANO, Luis. Pharmacoepidemiological study of the use of non-steroid antiinflamatory drugs in high-risk cardiovascular patients. Rev. perú. med. exp. salud publica [online]. 2013, vol.30, n.4, pp.626-629. ISSN 1726-4634.
In order to determine the frequency of extended use of non-steroidal anti-inflammatory drugs (NSAID) in Colombian patients with high cardiovascular risk (HCVR), a retrospective study was developed which identified HCVR patients who used NSAID for over five continuous months from January 2011 and March 2013. Patients chronically receiving nitrates, digitalis and clopidogrel and acetylsalicylic acid (ASA), known as HCVR, were identified. An analysis of the frequencies of use based on the co-medication received was performed. Concomitant use of NSAID was found in 0,35% of consumers of nitrates (average time: 9,5 ± 4,4 months), in 0,36% of consumers of clopidogrel and ASA (average time: 9,3 ± 3,4 months), and in 0,4% of consumers of digitalis (10,2 ± 4,6 months). It is concluded that there is a low proportion of chronic use of NSAID in high-risk cardiovascular patients.
Palabras clave : Cardiovascular diseases; Anti-Inflammatory agents, non-steroidal; Pharmacoepidemiology; Pharmacovigilance; Colombia.