SciELO - Scientific Electronic Library Online

vol.33 issue1GHRd3 polymorphism of growth hormone receptor gen in peruvian children with idiopathic short statureCharacteristics of mistreatment in medical students of a public university in Peru author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista Peruana de Medicina Experimental y Salud Publica

Print version ISSN 1726-4634


MARIN-MARIN, Diego  and  SOTO, Alonso. Comparison of prognostic scoring systems in the prediction of mortality and complications from sepsis. Rev. perú. med. exp. salud publica [online]. 2016, vol.33, n.1, pp.51-57. ISSN 1726-4634.

Objectives. To compare the Mortality in Emergency Department Sepsis (MEDS), Sepsis-related Organ Failure Assessment (SOFA), Acute Physiology and Chronic Health Evaluation (APACHE II), and Confusion, Urea, Respiratory rate, Blood pressure, 65 years of age and older (CURB-65) scoring systems for predicting mortality and complications in septic patients. Materials and methods. A prospective study of diagnostic test assessment was carried out. Scores were compared by analysis of receiver operating characteristic (ROC) curves corresponding to each score, with the development of death or complications as the dependent variable. Results. There were 265 patients included in the analysis; 155 (58.4%) patients died and/or presented complications. The multivariate analysis revealed variables associated with mortality and complications were age, oliguria, mental health impairment, acute lung injury, and the use of inotropes. Analysis of ROC curves showed the area below the ROC curve was 0.74 (95% CI: 0.68-0.80) for SOFA, 0.73 (95% CI: 0.67-0.79) for MEDS, 0.73 (95% CI: 0.66-0.79) for APACHE II, and 0.67 (95% CI: 0.60-0.73) for CURB-65, the latter being significantly lower than the first three. Conclusions. The MEDS, SOFA, and APACHE II are adequate scoring systems for predicting mortality and complications in septic patients. It is essential to utilize these scoring systems in emergency medical assistance in hospitals in Peru.

Keywords : Sepsis; Forecasting; diagnosis; Prognosis; mortality.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License