SciELO - Scientific Electronic Library Online

 
vol.33 número1Distribución espacial de los accidentes y enfermedades relacionados con el trabajo en el Perú, 2012-2014Intervención psicológica a candidatos de cirugía bariátrica en un hospital público de Brasil índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Compartir


Revista Peruana de Medicina Experimental y Salud Publica

versión impresa ISSN 1726-4634

Resumen

SILVERO-ISIDRE, Arturo et al. Acute toxicity of Xanthium spinosum leaves in BALB/C mice. Rev. perú. med. exp. salud publica [online]. 2016, vol.33, n.1, pp.113-119. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2016.331.1888.

The leaves of the Xanthium spinosum plant have been used culturally in Paraguay for their medicinal properties. Acute toxicity of mature leaf extract was evaluated. For the study, 35 Balb/c mice were selected and allocated into 7 groups, 6 test groups and 1 control group. The extract was prepared in concentrations of 6% and 9% (g/dL). The 6% concentration was administrated to 3 test groups and 9% concentration to the remaining 3 groups, with doses between 200 and 1000 mg/kg per mouse. After 14 days of observation, blood samples were taken for laboratory studies of urea and transaminases and organs were examined for pathological studies. There were increased levels of GOT and urea in the test groups compared to the control group. In conclusion, the consumption of mature leaf extract of Xanthium spinosum can cause hepatic damage.

Palabras clave : Xanthium spinosum; Acute toxicity; Plants; medicinal.

        · resumen en Español     · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons