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Revista Peruana de Medicina Experimental y Salud Publica
Print version ISSN 1726-4634
Abstract
SERMINI, Carmen Gloria; ACEVEDO, María José and ARREDONDO, Miguel. Biomarkers of metabolism and iron nutrition. Rev. perú. med. exp. salud publica [online]. 2017, vol.34, n.4, pp.690-698. ISSN 1726-4634. http://dx.doi.org/10.17843/rpmesp.2017.344.3182.
Iron deficiency anemia is the most common nutritional deficiency worldwide, and the most susceptible groups are infants, preschoolers, women of childbearing age, and pregnant women. It is therefore essential to understand the mechanisms of regulation of iron uptake, transport, and absorption at the cellular level, particularly in enterocytes, and to identify blood biomarkers that allow the evaluation of iron status. This review describes how iron absorption is regulated by intestinal epithelial cells, the main proteins involved (iron transporters, oxidoreductases, storage proteins), and the main blood biomarkers of iron metabolism.
Keywords : Iron; Intracellular Regulation; Biomarker; Reference value; Inflammation.