Abstract

SACSAQUISPE-CONTRERAS, Rosa  and  BAILON-CALDERON, Henri. Identification of carbapenem-resistant genes in enterobacteria from peruvian hospitals, 2013-2017. Rev. perú. med. exp. salud publica [online]. 2018, vol.35, n.2, pp.259-264. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2018.352.3829.

The global spread of carbapenemases is a significant public health concern. The aim of this report is to describe the presence of KPC-type carbapenem-resistant genes and enterobacteria isolated in 12 hospitals and forwarded to the Peruvian National Institute of Health’s National Infection Reference Laboratory during the period between 2013 and 2017. The strains were identified by conventional methods; antimicrobial resistance was determined by phenotypic and biochemical methods. The presence of resistant genes was detected by conventional PCR. Eighty-three (83) strains harboring carbapenemases were identified: 26 (31.3%) carrying the bla_KPC gene, 56 (67.5%) the bla_NDMgene, and one strain (1.2%) with the bla_IMP gene. This is the first report that shows the circulating carbapenemases genes in Hospitals in Peru of cases submitted for their confirmation to the National Reference Laboratory, so it is necessary to improve the surveillance to better understand their situation in our country.

Keywords : Carbapenems; Enterobacteriaceae infections; beta-Lactam Resistance; carbapenemase-producing Enterobacteriaceae; Peru.

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