Resumo

FLORES-ANGULO, Carlos et al. Blastic plasmacytoid dendritic cell neoplasm variant acute leukemia: case report. Rev. perú. med. exp. salud publica [online]. 2019, vol.36, n.2, pp.353-359. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2019.362.3779.

Blastic plasmacytoid dendritic cell blast neoplasm (BPDCN) is a rare and generally aggressive hematologic malignancy, requiring early recognition. Below is a description of the prolonged clinical course of a 60-year-old male patient with BPDCN from Venezuela, whose most relevant findings highlighted the presence of skin lesions, organomegaly, infiltration of the bone marrow and central nervous system. Systemic chemotherapy was prescribed after diagnosis; however, the patient died of respiratory complications during the induction phase of treatment. In this disease, it is necessary to establish the differential diagnosis with lymphoproliferative disorders, acute lymphoid and myeloid leukemias. The morphological analysis of neoplastic cells is, thus, an important aspect toward proper diagnostic guidance.

Palavras-chave : Blastic plasmacytoid dendritic cell neoplasm; hematologic malignancy; acute myeloid leukemia.

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