Abstract

AMPUERO, Angela; ROJAS, Rosario; RUIZ, Candy  and  HURTADO, Jasmin. Streptomyces sp. 6E3 antimicrobial activity isolated from mineral concentrate. Rev. perú. med. exp. salud publica [online]. 2020, vol.37, n.1, pp.110-114. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2020.371.4505.

The objectives of this study were to determine the antimicrobial activity of a culture of Streptomyces sp. 6E3 isolated from minerals against different pathogenic strains, to produce an extract and to estimate the minimum inhibitory concentration (MIC) of the fractions against methicillin-resistant Staphylococ cus aureus (MRSA). Streptomyces sp. 6E3 showed antimicrobial activity primarily against Staphylococcus aureus (S. aureus). Five of the six fractions presented antimicrobial activity and the most effective gave a MIC of 0.88 ug / mL against S. aureus ATCC 33862, 0.44 ug / mL against S. aureus ATCC 43300 and 1.76 ug / mL vs. a S. aureus MRSA strain. Streptomyces sp. 6E3 has an antimicrobial potential against S. aureus strains resistant to methicillin and non-resistant, being of interest carrying out of more studies on its active metabolites.

Keywords : Streptomyces; Minerals, Anti-infective agents; Cell extracts; Bacteria; Staphylococcus aureus; Biological Products; Microbial Sensibility Tests.

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