Abstract

GUEVARA-SILVA, Erik et al. Clinical characteristics and plasma exchange response in Guillain-Barré patients. Rev. perú. med. exp. salud publica [online]. 2021, vol.38, n.1, pp.89-94.  Epub Feb 01, 2021. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2021.381.6233.

The objective of the study was to describe the clinical characteristics, treatment response and possible associated factors of patients with Guillain-Barré syndrome at the National Institute of Neurological Sciences. A descriptive study on hospital discharges was conducted during the period 2017-2019. Treatment response was evaluated based on Hughes’ disability scale. From 31 patients 61.3% were males and the mean age was 50 years. At admission, 87.1% of patients were on grade 3 or 4 of Hughes scale, most of them with axonal compromise which was associated to disability. Only 22 patients received plasma exchange; 6 months thereafter, 90.9% of patients decreased by at least one degree in Hughes scale and 42.8% were left without disability. In conclusion, a male and axonal subtype predominance was found, been the latter associated to disability.

Keywords : Cerebrospinal Fluid; Axonal Neuropathy; Demyelinating Neuropathy; Poliradiculoneuropathy; Plasmapheresis; Peru; Plasmatic Therapeutic Exchange; Guillain-Barré Syndrome.

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