Abstract

CASTRO, Nataly Echevarria et al. Trends in drugs usage for COVID-19 during the first wave of the pandemic in a hospital in Lima, Peru. Rev. perú. med. exp. salud publica [online]. 2021, vol.38, n.4, pp.608-614.  Epub Dec 22, 2021. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2021.384.8820.

This study aimed to evaluate the pharmacological trends in patients with COVID-19 from a hospital in Peru during the first wave of the pandemic. Retrospective study conducted between April and September 2020. The medical records of patients hospitalized for COVID-19 pneumonia at the Dos de Mayo National Hospital (Lima, Peru) were reviewed. Of a total of 3103 patients, 381 medical records were included (77.4% male, median age: 44 years). The use of four prehospital drugs increased (azithromycin, ivermectin, corticosteroids, and ceftriaxone), while the in-hospital use of six drugs (ceftriaxone, azithromycin, hydroxychloroquine, ivermectin, corticosteroid pulse, and prophylactic anticoagulation) decreased and in-hospital anticoagulation use decreased. These findings suggest that the management of COVID-19 has varied during the first wave of the pandemic, typically increasing prehospital drug use and decreasing inpatient use.

Keywords : COVID-19; Pneumonia; Therapeutics; Drugs Utilization; Hospitalization; Epidemiologic Factors; Anti-bacterial Agents; Dexamethasone; Peru; Trends.

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