Resumo

GONZALES-RODRIGUEZ, Arturo Octavio; CASTILLO HORNA, Javier Ignacio  e  GONZALES ESCALANTE, Edgar. Identification of multidrug-resistant enterobacteriaceae in fecal samples from infants residing in Talara, Piura, Peru. Rev. perú. med. exp. salud publica [online]. 2022, vol.39, n.4, pp.456-462.  Epub 09-Dez-2022. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2022.394.11870.

Fecal colonization by antimicrobial-resistant bacteria in infants is a potential risk for future antibiotic therapy. We aimed to determine the sociodemographic characteristics and frequency of infants who were fecal carriers of ciprofloxacin-resistant enterobacteriaceae (FCCRE) and their associated resistance genes. We analyzed fecal samples from 41 infants from the district of Talara, Piura, Peru in 2019. The presence of 3 quinolone resistance genes was evaluated: aac(6’)-Ib-cr, qnrB and oqxA as well as of 2 beta-lactamase genes: bla CTX-M,bla PER-2. We found that 68% of infants were FCCRE, Escherichia coli (83.3%) was the most frequent bacteria. The genotypic analysis detected: oqxA (41.1%), qnrB (26.7%), aac(6’)-Ib-cr (20%) and the bla CTX-M gene (93.3%) of the isolates with beta-lactamases. The high frequency of FCCRE alerts us of the potential risk of this antibiotic family becoming less useful over time.

Palavras-chave : Newborn, Escherichia coli; Drug Resistance; beta-Lactamases; Quinolones; Peru; Coliforms.

        · resumo em Espanhol     · texto em Espanhol | Inglês     · Inglês ( pdf ) | Espanhol ( pdf )