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Revista Peruana de Medicina Experimental y Salud Publica

Print version ISSN 1726-4634

Abstract

PEINADO, Jesus et al. Association between overweight/obesity and multidrug-resistant tuberculosis. Rev. perú. med. exp. salud publica [online]. 2023, vol.40, n.1, pp.59-66.  Epub Mar 30, 2023. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2023.401.12138.

Objective.

To evaluate the association between overweight/obesity and multidrug resistance in patients with and without a history of tuberculosis treatment.

Materials and methods.

Cross-sectional study of secondary data from a tuberculosis cohort, which included anthropometric and drug-sensitivity testing data at the baseline visit of patients with and without previous tuberculosis treatment.

Results.

We evaluated 3,734 new cases and 766 with a history of having received treatment for tuberculosis. Overweight/obesity was not associated with multidrug resistance in patients with a history of tuberculosis treatment, with a prevalence ratio of 0.97 and a 95% confidence interval of 0.68-1.38.

Conclusions.

Overweight/obesity is not associated with multidrug resistance in tuberculosis. Overweight/obesity is a dynamic process that may influence the relationship between the immune system and the metabolic system.

Keywords : Tuberculosis; Overweight; Obesity; Multidrug Resistance; Peru.

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