Abstract

CARRASCO-OROS, Lisbeth Varenia et al. Characteristics of hemolytic uremic syndrome in patients from a pediatric hospital in Peru, 2010-2020. Rev. perú. med. exp. salud publica [online]. 2023, vol.40, n.2, pp.207-212.  Epub June 30, 2023. ISSN 1726-4634.  http://dx.doi.org/10.17843/rpmesp.2023.402.12708.

This study aimed to describe the clinical-epidemiological, laboratory, treatment, and follow-up characteristics of patients with hemolytic uremic syndrome (HUS). The medical records of patients with HUS hospitalized at the Instituto Nacional de Salud del Niño-Breña (INSN-B) (Lima, Peru) were reviewed. We evaluated 83 patients. The median age was 22 months (interquartile range: 14 to 30 months). Of the sample, 71.1% (59) registered previous use of antibiotics. Seventy-two (86.8%) had oligoanuria and 62 (74.6%) had diarrhea. Five cultures were positive (two enterohaemorrhagic Escherichia coli). Forty-nine (59%) required renal replacement therapy. No patient died during hospitalization. At one year of follow-up, seven patients developed post-HUS nephropathy. In conclusion, in INSN-B, the median age was like previous years and there was a higher frequency of oligoanuria, and renal replacement therapy compared to previous reports.

Keywords : Hemolytic uremic syndrome; Renal Replacement Therapy; Child, Peru.

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