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Revista Peruana de Medicina Experimental y Salud Publica
Print version ISSN 1726-4634On-line version ISSN 1726-4642
Abstract
APARCO, Juan Pablo et al. Iron status and hemoglobin adjustment by altitude to define anemia in children aged 6 to 8 months living in Lima, Arequipa, Cusco and Puno. Rev. perú. med. exp. salud publica [online]. 2023, vol.40, n.4, pp.395-405. Epub Dec 18, 2023. ISSN 1726-4634. http://dx.doi.org/10.17843/rpmesp.2023.404.12573.
Objective.
To describe the iron status profile and to propose hemoglobin adjustment factors for altitude for children aged 6 to 8 months in Lima, Arequipa, Cusco and Puno.
Materials and methods.
Cross-sectional study in children aged 6 to 8 months from four cities. We measured hemoglobin and other iron biomarkers, C-reactive protein (CRP), among others. To estimate the adjustment equation, we applied an exponential regression. We excluded children with iron deficiency (ID) and/or inflammation.
Results.
The proportions of ID were higher in Puno and Arequipa, while inflammation did not exceed 19% in any of the cities. Hemoglobin showed an exponential increase at higher altitude. The adjustment equation was: 10.34249 x (1.00007 ^ Alt).
Conclusions.
Children residing in Arequipa and Puno showed higher rates of ID and lower iron reserves; furthermore, the increase in hemoglobin by altitude was exponential, showing the need to adjust hemoglobin at altitude.
Keywords : Child; Anemia; Altitude; Iron-Deficiency, Peru.