Abstract

LEMOR, Alejandro. Relationship between advanced maternal age and neonatal morbidity in the Hospital Nacional Arzobispo Loayza between January and October 2012. Horiz. Med. [online]. 2014, vol.14, n.2, pp.22-26. ISSN 1727-558X.

Objective: Determine the relationship between advanced maternal age and neonatal morbidity in the Hospital Nacional Arzobispo Loayza. Material and Methods: Cohort study, comparative, analytical, retrospective. A total of 2771 infants between January and October 2012 were included in the study; of which 460 were born of mothers aged over 35 and 2311 of mothers between 20 and 34 years. Statistical analysis used SPSS 21.0 and included the chi-square test, considering a p value of <0.05 for statistical significance. Results: 1.3% of newborns of older mothers had trisomy 21, compared with 0.13% in mothers aged 20 to 34 years (p <0.001, RR: 10.16, 95% CI 2.5 - 40.8). The cesarean delivery accounted for 51.52% in the group of aged over 35 and 37.78% in the control group (p <0.001, RR 1.75, 95% CI 1.43 - 2.14). There was no significant difference for other morbidities in both groups; hyaline membrane disease (p = 0.824), respiratory distress syndrome (p = 0.448) and neonatal sepsis (p = 0.309). Conclusions: Advanced maternal age was associated with a higher rate of C-sections and a higher risk of having a child with Down syndrome. There was no evidence that advanced maternal age is associated with increased neonatal morbidity.

Keywords : mechanical ventilation; neonatal; neonatal care.

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