Abstract

OCHOA ALLEMANT, Pedro et al. Comparison of single versus triple dose of cefazolin in antibiotic prophylaxis for caesarean section. Horiz. Med. [online]. 2014, vol.14, n.3, pp.37-43. ISSN 1727-558X.

Objective: To compare the effectiveness of single dose versus triple dose of Cefazolinas prophylactic antibiotics in women undergoing cesarean section. Material and Methods: An observational, analytic, retrospective, cross sectional comparative study. Eighty two medical records of women undergoing caesarean section who received either single dose or triple dose in the Almenara Irigoyen Hospital were included. Women were compared on the basis of development of postoperative infections. Results: The study groups did not have statistically significant differences in the incidence of total infections (9,3% vs 16,4%, p= 0,422), wound infections(7% vs 12,8%, p= 0,793), endometritis (0% vs 2,6%, p= 1,116) and urinary tract infection(2,3% vs 0%, p= 0,918). Conclusion: A single prophylaxis dose of Cefazolin was as effective as triple dose in preventing post-caesarean infectious morbidity.

Keywords : Cefazolin; antibiotic prophylaxis; caesarean section; post-caesarean infection.

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