Abstract

LAVADO LANDEO, Lincoln. Treatment of Staphylococcus aureus keratitis with 0.2% topical linezolid. Horiz. Med. [online]. 2015, vol.15, n.3, pp.46-50. ISSN 1727-558X.

Objective: To reportthe use of 0.2% topical linezolid in the treatment of Staphylococcus aureuskeratitis with successful results. Material and Methods: All cases were viewed in Centro Vision, here they underwent a complete ophthalmic examination and were diagnosed with Staphylococcus aureus keratitis based on a microbiological study. In both cases we began with the gold standard therapy based on fortified topical drops of vancomycin and an aminoglycoside. Due to ineffective action and/or poor tolerance of vancomycin, we decided to use topical linezolid. Results: Two female patients with Staphylococcus aureus keratitis received ocular 0.2% topical linezolid every hour. In both cases we saw a marked clinical improvement and a good tolerance to this antibiotic. Conclusion: 0.2% Topical linezolid is an effective and well tolerated antibiotic when used in the treatment of Staphylococcus aureus keratitis. It is more comfortable and less toxic than topical vancomycin. (Horiz Med 2015; 15(3):46-50)

Keywords : Bacterial keratitis; Staphylococcus aureus; vancomycin; linezolid.

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