Abstract

RUIZ-MORI, Enrique; AYALA-BUSTAMANTE, Leonor; BURGOS-BUSTAMANTE, Jorge  and  PACHECO ROMAN, Cristian. Chemotherapy-induced cardiotoxicity at the Instituto Nacional de Enfermedades Neoplásicas 2012-2016. Horiz. Med. [online]. 2017, vol.17, n.3, pp.24-28. ISSN 1727-558X.  http://dx.doi.org/10.24265/horizmed.2017.v17n3.05.

objective: To report the frequency of cardiac adverse effects (cardiotoxicity) induced by chemotherapy in patients of the Instituto Nacional de Enfermedades Neoplásicas during the period 2012-2016. Materials and methods: The study had a non-experimental, descriptive and retrospective design. The study population consisted of patients treated at the Cardiology Service due to cardiovascular discomfort during chemotherapy. Results: Nine hundred eighty-five (985) evaluations were performed because of cardiac symptoms in patients undergoing antineoplastic treatment. Among the oncological treatment-related cardiovascular adverse effects, cardiac arrhythmias were the most frequent ones (41.2%), episodes of angina pectoris were in the second place with 18.7%, and heart failure had a frequency of 4.9%. The most frequent arrhythmia was sinus bradycardia (55.9%), followed by symptomatic sinus tachycardia (17.7%) and, in the third place, atrial fibrillation (12.0%). Conclusions: Cardiac arrhythmia was the most frequent adverse effect induced by oncological treatment, with asymptomatic sinus bradycardia being the most prevalent one

Keywords : Cardiotoxicity; chemotherapy; cardiac arrhythmia; cardio-oncology.

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