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vol.18 issue3Diagnostic accuracy and reliability of the neurological and arterial tests according to the IWGDF guidelines in the diagnosis of diabetic peripheral neuropathy and peripheral arterial disease in type 2 diabetic patients attending the primary health care author indexsubject indexarticles search
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Horizonte Médico (Lima)

Print version ISSN 1727-558X


ALVAREZ- ANGELES, M et al. Hematologic and biochemical characteristics in patients with and without type 2 diabetes mellitus undergoing hemodialysis during a one-year follow-up period. Horiz. Med. [online]. 2018, vol.18, n.3, pp.6-11. ISSN 1727-558X.

Objective: To report if there are hematologic and biochemical differences among patients with and without type 2 diabetes mellitus (T2DM) undergoing hemodialysis (HD). Materials and methods: An observational, retrospective, cohort study of patients treated in the Renal Health Program at the Centro de Prevención de Enfermedad Renal S.A.C. (CENPER) in Lima, Peru. The hematologic and biochemical parameters of 3 patients with T2DM and 3 patients without T2DM undergoing HD were compared. Results: Significant differences (p < 0.05) were found in the lymphocyte percentage, lymphocyte/monocyte ratio (LMR), hemoglobin and hematocrit concentration (lower in diabetic patients), monocyte percentage, and neutrophil/ lymphocyte ratio (NLR) (higher in diabetic patients). In the biochemical parameters, the only significant difference was found in the glutamic-oxaloacetic transaminase (GOT) value, which was higher in the diabetic patients compared with the non-diabetic patients (p < 0.005). Conclusions: Diabetes is an important factor linked to inflammation, anemia, lymphopenia and monocytosis in patients undergoing HD. The LMR was the most powerful marker of inflammation in this patient series. Larger-scale studies are required to verify this evidence.

Keywords : Type 2 diabetes mellitus; Metabolism; Hemodialysis; Blood; Immunology.

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