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Horizonte Médico (Lima)
Print version ISSN 1727-558X
Abstract
BARRERA-ESPINOZA, Richar William et al. Factors associated with nonadherence to antiretroviral therapy in people with HIV/AIDS. Horiz. Med. [online]. 2021, vol.21, n.4, e1498. Epub Dec 03, 2021. ISSN 1727-558X. http://dx.doi.org/10.24265/horizmed.2021.v21n4.09.
Objective:
To determine the association that social, clinical and therapeutic factors and coexisting diseases have with nonadherence to antiretroviral therapy in people with HIV/AIDS in 2018.
Materials and methods:
A cross-sectional study conducted with a sample of 117 people with HIV/AIDS on antiretroviral therapy at the Hospital Daniel Alcides Carrión. The Questionnaire for the Assessment of Adherence to Antiretroviral Therapy (CEAT-VIH) adapted for use in Peru was administered. The IBM SPSS Statistics V23 and logistic regression were used for the statistical analysis.
Results:
Seventeen point one zero percent (17.10 %) of the patients did not adhere to the therapy and 82.90 % adhered to their prescribed treatment. The variables most likely to predict nonadherence were sex (OR = 16.175, p value = 0.023) and HIV/AIDS- related comorbidities (OR = 9.556, p value = 0.003). The initial viral load variable (OR = 0.152, p value = 0.030) acts as a protector because there is a greater probability of treatment adherence.
Conclusions:
Male sex and HIV/AIDS-related comorbidities are associated with the nonadherence to antiretroviral therapy. The initial viral load variable acts as a protector for treatment adherence.
Keywords : Treatment adherence and compliance; Antiretroviral therapy; HIV; Acquired immunodeficiency syndrome.