Abstract

VEGA-FERNANDEZ, Jorge Arturo; SUCLUPE-CAMPOS, Danny Omar  and  AGUILAR-GAMBOA, Franklin Rómulo. Ivermectin: an antiparasitic drug to fight SARS-CoV-2?. Horiz. Med. [online]. 2021, vol.21, n.4, e1276.  Epub Dec 03, 2021. ISSN 1727-558X.  http://dx.doi.org/10.24265/horizmed.2021.v21n4.12.

The global spread and lethality of SARS-CoV-2 prompt the urgent need to develop an appropriate therapeutic strategy to control COVID-19 cases. The development of new drugs to fight this novel virus is urgent due to its rapid spread. Parallel alternatives have been proposed by using drugs already available for similar purposes. This review article describes the antiviral potential of ivermectin as well as its mechanisms of action against some viruses, and discusses its probable use to fight SARS-CoV-2.

Keywords : Ivermectin; Coronavirus infections; COVID-19; Nucleocytoplasmic transport proteins; Receptors, nicotinic; Pharmacology; Clinical trial.

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