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Acta Médica Peruana

On-line version ISSN 1728-5917


SUAREZ ALVARADO, Edwin  and  HEINIKE YANEZ, Hugo. Recurrent meningiomas: Associated factors. Acta méd. peruana [online]. 2010, vol.27, n.1, pp.12-21. ISSN 1728-5917.

Objective: To identify factors related with recurrence of intracranial meningiomas operated at the Instituto Nacional de Enfermedades Neoplásicas (Peruvian National Cancer Institute). Material and method: Retrospective, comparative, analytical, case control study. Patients operated who had an anatomopathological diagnosis of meningioma and who underwent a post-operative control after five years were included. Results: Total surgical resections were performed in 36 patients, and subtotal resections were performed in 19 patients. Nearly sixty per cent (57.8%) of patients undergoing subtotal resections developed recurrences, as well as 33.3% of those who underwent total resections, giving a 2.7 odds ratio (OR) and p<0.05. Recurrences were most frequently observed in male patients, with a 1.7 OR. Age of recurrence was 43.9 ± 16.3 years compared to 40.85 ± 17.7 in the control group. Time for recurrence was on average 30.7 ± 16.3 months. The location of most frequently recurring meningiomas was the temporal area. There is no predominance of any type of meningioma with respect to recurrence. Conclusions: The factor for recurrence was surgical resection, and it was found that a patient undergoing a subtotal surgical resection had 2.7 times more likelihood for developing meningioma recurrence compared to total surgical resection. Male patients recurred more frequently. Average age of patients was 43.9 years. Average time for recurrence was 30.7 months.

Keywords : Meningioma; meningeal neoplasms; nervous system neoplasms.

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