Resumen

AMADO-TINEO, José Percy; VASQUEZ-ALVA, Rolando; KRAENAU-ESPINAL, Erwin  y  OSCANOA-ESPINOZA, Teodoro Julio. Potentially inappropriate medication as a risk factor for delirium in elderly, in an emergency service. Acta méd. peruana [online]. 2015, vol.32, n.4, pp.221-228. ISSN 1728-5917.

Objective. To evaluate the association of delirium (acute confusional state) with potentially inappropriate medication in older adults. Patients and MethOd. Analytical study of cases and controls. Systematic random sampling. Case: elderly patients with delirium. Participants: 102 cases and 136 controls; patients 65 years or older, admitted to the emergency service for adults Edgardo Rebagliati Martins National Hospital, in Lima. Interview and evaluate the patient or caregiver to income. Instruments: CAMICU and STOPP. Results. 731 drugs were prescribed in 238 patients; three drugs per patient, on average; the most common: enalapril, furosemide and acetylsalicylic acid. Potentially inappropriate medication in 24.6% (30% of cases and 20% of controls; p = 0.14) were found. They were more often: glibenclamide, digoxin (125 µg/d), shortacting nifedipine and diazepam; according to the pharmacological group, employees for the nervous system. The factors that had a significant association (p < 0.05) with delirium were: living alone, institutionalized, hospitalized during the previous year, comorbidity, history of cerebrovascular disease, dementia, functional dependency, moderate to severe dehydration, and infection at admission to the emergency. It was obtained odds ratio > 1.0 for: high school degree or less education, history of cerebrovascular disease, liver cirrhosis, dementia and moderate to severe dehydration at income. COnClusiOns. They are risk factors for delirium (acute confusional state): high school degree or less education, history of cerebrovascular disease, liver cirrhosis, dementia and moderate to severe dehydration. The potentially inappropriate medication was not a risk factor for delirium in older adults.

Palabras clave : inappropriate prescribing; delirium; acute confusional state; elderly.

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