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Acta Médica Peruana
On-line version ISSN 1728-5917
Abstract
GASTELO-ACOSTA, Rosy M; DIAZ-SIPION, Roberto S and MAGUINA VARGAS, Ciro. Carbapenemases in non-fermenting Gram-negative bacteria isolated in critical care services from the Lambayeque Regional Hospital, December 2014 - July 2015. Acta méd. Peru [online]. 2016, vol.33, n.3, pp.183-188. ISSN 1728-5917.
Objective: To determine the presence of carbapenemase producing non-fermenting Gram negative bacteria in critical care and emergency services from the Lambayeque Regional Hospital, December 2014 - July 2015. Material and methods: We included all isolates of non-fermenting Gram negative bacteria from clinical samples in the aforementioned services. Carbapenemase detection was performed in a two-step fashion: first, suspected samples were selected using the Kirby Bauer method. These samples underwent three further assessments, double disk approximation, modified Hodge, and Blue Carba tests. Results: Fifty bacterial isolates from secretion and fluid samples taken from patients with a presumptive diagnosis of infectious conditions were analyzed, and 48% of these samples were positive for the presence of carbapenemases. All Acinetobacter baumanii strains (21/21) had oxacillin-type carbapenemases and 3/29 Pseudomonas aeruginosa strains had metallo-betalactamase carbapenemases. Conclusions: Almost half of the isolated strains produced carbapenemases. It is necessary to perform surveillance activities on these strains and to have a firm policy for controlling antimicrobial resistance in order to prevent the expansion of these conditions
Keywords : Gram-negative bacteria; drug resistance; microbial, acinetobacter; pseudomonas.