Abstract

PEREZ, Giancarlo; MAQUERA-AFARAY, Julio; LINARES, Sandra  and  CASTILLO, Raúl. Burkitt´s lymphoma of the tonsil in HIV patient, associated to occipital tumor and osteolytic lesions in the cranial vault. Acta méd. Peru [online]. 2017, vol.34, n.1, pp.52-56. ISSN 1728-5917.

Burkitt’s lymphoma affecting the tonsils represents 5% of primary extranodal non-Hodgkin lymphomas and it usually occurs in HIV-infected patients with high CD4+ counts and chronic viremia. We report a case of a 37 year-old male diagnosed with HIV infection less than one year ago, who had irregular adherence to HAART. This patient presented with an ulcerated and necrotic lesion in the left tonsil, and he also had osteolytic lesions in the cranial vault, with involvement of the soft tissues, predominantly in the occipital area. His CD4+ count was 50 cells/mm3 and the viral load (HIV-RNA) was 1’250,000 copies/mL. The biopsy of tonsil was reported as compatible with Burkitt’s lymphoma. The patient was started with chemotherapy using CODOX-M/IVAC (cyclophosphamide, vincristine, doxorubicin and methotrexate + intrathecal cytarabine); however, the overall clinical response was poor despite the good virological suppression

Keywords : Burkitt lymphoma; HIV; Cranial skull.

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