Abstract

MORENO-LOAIZA, Milagros  and  MORENO-LOAIZA, Oscar. Clinical and epidemiologycal characteristics of candidemia at a tertiary hospital from Southern Peru, 2011-2014. Acta méd. Peru [online]. 2017, vol.34, n.4, pp.289-293. ISSN 1728-5917.

Objective: To describe the clinical and epidemiological characteristics of candidemia in a tertiary hospital in southern Peru during the years 2011-2014. Materials and methods: Retrospective study conducted at the Carlos Alberto Seguin Escobedo National Hospital (HNCASE) in the city of Arequipa, Peru. We reviewed the medical records of patients who had at least one positive blood culture for Candida sp. The characteristics evaluated were age, sex, service of origin, alteration of the immune system, previous colonization by fungi, neoplasia, chronic renal failure, diabetes, use of corticosteroids, use of invasive device, exposure to broad spectrum antibiotics, mechanical ventilation, hemodialysis, total parenteral nutrition, severe sepsis, previous surgery, and days of hospital stay. Results: Between 2011 and 2014, 71 patients presented candidemia. The services with the highest number of infected patients were Intensive Care Unit (ICU) 17 (23.94%) and Internal Medicine 17 (23.94%). The isolated species were C. albicans 33 (46.48%), C. paralopsilosis 16 (22.54%), C. glabrata 9 (12.68%), C. tropicalis 8 (11.27%), C. guillermondi 4 (5.63%), and C. krusei 1 (1.41). The most frequent characteristics of these patients were the use of invasive device (88.73%), exposure to broad spectrum antibiotics (83.1%). Conclusion: Candidiasis is a rare disease in HNCASE produced mainly by C. albicans, C. paralopsilosis, and C. glabrata. The most frequent characteristics of these patients were the use of invasive devices and exposure to broad spectrum antibiotics

Keywords : Candidemia; Candida albicans; Candida glabrata.

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