Resumen

HUAMANI, Charles; ROJAS, Edgard  y  INCA, José. Highly active multiple sclerosis: is it possible to start early therapy with highly efficacious drugs?. Acta méd. Peru [online]. 2017, vol.34, n.4, pp.301-308. ISSN 1728-5917.

Multiple sclerosis (MS) is a chronic central nervous system (CNS) disease that may have variable clinical manifestations, it may progress as flares, leaving sequels between such flares, and have a slow disabling course. However, in some persons, MS flares lead to marked CNS involvement, rapid disability progression, and to other factors that lead to a poor prognosis for this disease. Although there is no consensus for a definition, these features may indicate that the condition is a highly active form of MS. Being able to early identify highly active MS would allow us to have individualized therapy and use highly efficacious drugs. In this paper we describe how difficult it is to have an adequate definition of highly active MD, and the need for early start using highly efficacious drugs for these highly active forms of MS that occur as early flares of the disease

Palabras clave : Multiple sclerosis; Disabled persons; Chronic disease.

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