SciELO - Scientific Electronic Library Online

vol.36 issue3Effects of a lubricating emulsion upon symptoms, eye surface damage, and tear film instability in patients with dry eye associated to the computer vision syndromeEffect of Rivers Protocol in improving hemodynamics and oxygenation in patients with septic shock due to severe pneumonia in EsSalud III Hospital in Chimbote author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Acta Médica Peruana

On-line version ISSN 1728-5917


GARIZA, Ana C et al. Physical growth in children with salt-wasting adrenal hyperplasia during their first two years of life in the Peruvian National Children’s Health Institute. Acta méd. Peru [online]. 2019, vol.36, n.3, pp.209-216. ISSN 1728-5917.

Objective: To describe physical growth features in children with salt-wasting congenital adrenal hyperplasia (CAH) during their first two years of life, in the Endocrinology Service of the Peruvian National Children’s Health Institute (CHI) in Lima, Peru. Materials and Methods: This is a retrospective, observational, and descriptive study. Fifty-five children with CAH underwent follow-up in the Endocrinology Service of the CHI from 2000 to 2016; data such as body weight and height were collected at birth time and every six months, as well as age at diagnosis, hydrocortisone and fludrocortisone doses, and growth velocity. Results: Fifty-five children with salt-wasting CAH were assessed, the diagnosis was more promptly made in females (median: 21 days) compared to males (median: 52 days). At birth, their average length was 0.07 ± 0.75 SD; at 6 months it was -1.67 ± 1.33 SD, and male subjects were more affected (-2.29 ± 1.18 SD; p= 0.022); at 12 months, this parameter was -1.84 ± 1.27 SD, and recovery was observed at 24 months (-1.51 ± 1.10 SD). Growth velocity values were -1.03 ± 1.62 SD and -0.89 ± 1.06 SD in the first and second years of life, respectively. Conclusions: Children with salt-wasting CAH who were followed-up at CHI had shorter length at 6- and 12- months of age, and their recovered at 24-monbths.

Keywords : Adrenal hyperplasia, congenital; Child; Growth and development; Glucocorticoids.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License