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Acta Médica Peruana

On-line version ISSN 1728-5917


DE LA CRUZ-ARMIJO, Frank et al. Successful treatment of hemophagocytic syndrome secondary to Epstein-Barr virus infection: Report of a case. Acta méd. Peru [online]. 2019, vol.36, n.3, pp.227-230. ISSN 1728-5917.

We present the case of a six-year old male patient who presented with hemophagocytic syndrome secondary to Epstein Barr virus infection. The patient had fever, hepatosplenomegaly, liver failure, coagulation, ferritin, and triglyceride disorders, as well as a significant reduction of all blood cell populations. Bone marrow aspirate revealed the presence of autophagocytosis, so specific therapy according to the HLH 2004 protocol was started, and the patient satisfactorily responded after four weeks. Nowadays the patient still attends his control appointments, no relapse has been detected, and both his development and growth are adequate. Few reports on hemophagocytic syndrome have been published in Peru; however, this condition may be more frequent than previously thought. Therefore, it is important to report such cases, particularly successful experiences, aiming to improve management of this condition.

Keywords : Lymphohistiocytosis, hemophagocytic; Epstein-Barr virus infections; Child; Lymphopenia.

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