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Acta Médica Peruana
On-line version ISSN 1728-5917
Abstract
RAMOS-RAMIREZ, Keyla E. and SOTO, Alonso. Sarcopenia, in-hospital mortality and prolonged hospital stay in elderly subjects admitted to a Peruvian reference hospital. Acta méd. Peru [online]. 2020, vol.37, n.4, pp.447-454. ISSN 1728-5917. http://dx.doi.org/10.35663/amp.2020.374.1071.
Objective:
to determine whether sarcopenia is an associated factor to in-hospital mortality and prolonged hospital stay (PHS) in elderly subjects admitted to Hipolito Unanue National Hospital (HUNH) between December 2019 and March 2020.
Materials and methods:
this is an observational prospective cohort study performed in elderly subjects admitted to the Medicine Service in HUNH. Crude and multivariate analysis were performed using Poisson regression, aiming to determine a relationship between sarcopenia and in-hospital mortality and PHS by relative risk (RR).
Results:
nearly half of all patients (49.4%) in the study had sarcopenia, 12.3% died, and 32.5% had PHS. The crude analysis showed an association between sarcopenia and in-hospital mortality (RR: 4.69, 95% CI: 1.62-13.10, p=0.004); nonetheless, when an adjusted analysis was performed, this significance value got lost (p=0.097). No significant association was found between sarcopenia and PHS (p=0.673).
Conclusion:
sarcopenia is a condition affecting a large proportion of hospitalized elderly subjects, and it is associated to a higher risk of dying during hospitalization. There is no association between sarcopenia and PHS.
Keywords : Sarcopenia; Mortality; Length of stay; Aged.