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Acta Médica Peruana

On-line version ISSN 1728-5917


ESPIRITU ROJAS, Elizabeth; ZUMBA, Karin  and  GUILLEN-PINTO, Daniel. Intraventricular hemorrhage in premature infants under 28 weeks in general hospital of Lima, 2013 - 2017. Acta méd. Peru [online]. 2021, vol.38, n.1, pp.7-16.  Epub May 23, 2021. ISSN 1728-5917.


: To determine the incidence and clinical characteristics of intraventricular hemorrhage (IVH) in premature infants younger than 28 weeks, born in a general hospital.

Material and Methods

: Observational, descriptive, longitudinal, retrospective cohort study, which included premature infants less than 28 weeks gestational (PT28), who survived the first day of life, examined with brain ultrasound and cared for in the neonatal unit of Hospital Cayetano Heredia del 2013 to 2017. Neonates with brain malformations and those with incomplete perinatal data were excluded.


: 84 PT28 were identified, of which 72 were included, twelve were excluded due to malformations and lack of data. The male / female ratio was 1.6. The frequency of HIV was 58.3% (42/72). 52.4% (22/42) were found in the early form and 47.6% (20/42) in the late form. Severe grades were present in 64% (27/42). Posthemorrhagic hydrocephalus occurred in 26% (11/42) and venous hemorrhagic infarction in 21.4% (9/42). 51 patients died, with a fatality rate of 76.1% (32/42).


: HIV was very frequent, severe and lethal in the TST28, half of the cases occurred in the first three days and the rest during the first two weeks of life. Associated factors were lower birth weight, labor, and pneumothorax.

Keywords : Prematurity; intraventricular hemorrhage; neonate.

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