Resumo

VIRU-LOZA, Manuel André. Vitamin D deficiency associated with hyperphosphatemia in children. Acta méd. Peru [online]. 2021, vol.38, n.2, pp.117-122. ISSN 1728-5917.  http://dx.doi.org/10.35663/amp.2021.382.1909.

Children with vitamin D deficiency can have normal or high phosphorus despite having a high parathyroid hormone test (PTH). Pseudohypoparathyroidism (PHP) is characterized by hyperphosphatemia. The similarity that can occur between vitamin D deficiency associated with hyperphosphatemia and PHP makes it important to review case reports of vitamin D deficiency associated with hyperphosphatemia to understand why this association may occur and what is the relevance of studying the vitamin D level in children with suspected PHP. The aim of this review was to identify reports of children with vitamin D deficiency associated with hyperphosphatemia and to discuss the mechanisms of this association. Reports of 7 children cases were identified. Vitamin D deficiency could reduce the phosphaturic response to elevated PTH. It is concluded that it is important to rule out vitamin D deficiency in all children with suspected PHP.

Palavras-chave : Vitamin D; Vitamin D Deficiency; Hyperphosphatemia; Rickets; Pseudohypoparathyroidism; Parathyroid Hormone; Hypocalcemia; Child.

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